Cinobufotalin
Cinobufotalin, a cardiac toxin from toad venom, exhibits anti-hepatocellular carcinoma (HCC) activity by inducing growth arrest and apoptosis via ceramide generation in vitro. It reverses multidrug resistance by downregulating P-gp and MRP-1, and enhances the maturation and function of dendritic cells from chronic hepatitis B patients, potentially boosting antiviral immunity.
Product Specifications
CAS Number
1108-68-5
Product Name Alternative
P-gp, Pgp, Akt, Cinobufotalin, ILReceptor, IL Receptor, Inhibitor, inhibit, MRP1, MRP-1
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.92% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM) ; DMSO:50 mg/mL (109.04 mM)
Smiles
CC (=O) O[C@H]1[C@H]2O[C@]22[C@@H]3CC[C@]4 (O) C[C@@H] (O) CC[C@]4 (C) [C@H]3CC[C@]2 (C) [C@H]1c1ccc (=O) oc1
Molecular Formula
C26H34O7
Molecular Weight
458.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Tumor necrosis factor receptor superfamily member 19L (Relt)
Tumor necrosis factor receptor superfamily member 19L (Relt)
