Neoline
Neoline, an active component from A. venetum root (PA), alleviates oxaliplatin-induced peripheral neuropathy in murine models by inhibiting Nav1.7 voltage-gated sodium channels. This small molecule serves as a useful analytical marker for PA product quality in neuropathic pain research, with applications in both in vivo behavioral studies and in vitro electrophysiology assays.
Product Specifications
CAS Number
466-26-2
Product Name Alternative
Bullatine B, Inhibitor, pain, neuropathic, neuropathy, Neoline, Nav1.7 channel, inhibit, peripheral, oxaliplatin-induced, SodiumChannel, Sodium Channel
Field of Research
Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.43 mM) ; DMSO:200 mg/mL (457.07 mM)
Smiles
[H][C@]12C[C@]3 ([H]) [C@] ([H]) ([C@H]1O) [C@] (O) (C[C@@H]2OC) [C@@]1 ([H]) [C@H] (OC) [C@@]2 ([H]) C33[C@@H] (O) CC[C@@]2 (COC) CN (CC) [C@]13[H]
Molecular Formula
C24H39NO6
Molecular Weight
437.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
22379061 1.0 µg DNA
GOLGA6L16P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
JOT-EK0341Hu-02 48 Well
Human neutrophil peptide 1-3,HNP1-3 ELISA KIT
Sign In for Pricing
View Details JOT-EK0341Hu-01 96 Well
Human neutrophil peptide 1-3,HNP1-3 ELISA KIT
Sign In for Pricing
View Details GTR15187022 1 Vial
Lentiviral mouse Frs3 shRNA (UAS) - Lentiviral mouse Frs3 shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details