D-tetrahydropalmatine
D-Tetrahydropalmatine is a selective inhibitor of the organic cation transporter 1 (OCT1) . It effectively blocks monocrotaline (MCT) uptake in vitro, as demonstrated in MDCK-hOCT1 cells and primary rat hepatocytes, thereby reducing MCT-induced cytotoxicity. This makes it a valuable pharmacological tool for studying hepatic drug transport and toxin metabolism in experimental models.
Product Specifications
CAS Number
3520-14-7
Product Name Alternative
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.63 mM) ; DMSO:25 mg/mL (70.34 mM)
Smiles
[H][C@@]12Cc3ccc (OC) c (OC) c3CN1CCc1cc (OC) c (OC) cc21
Molecular Formula
C21H25NO4
Molecular Weight
355.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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