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D-tetrahydropalmatine

D-Tetrahydropalmatine is a selective inhibitor of the organic cation transporter 1 (OCT1) . It effectively blocks monocrotaline (MCT) uptake in vitro, as demonstrated in MDCK-hOCT1 cells and primary rat hepatocytes, thereby reducing MCT-induced cytotoxicity. This makes it a valuable pharmacological tool for studying hepatic drug transport and toxin metabolism in experimental models.

Product Specifications

CAS Number

3520-14-7

Product Name Alternative

Dopamine Receptor, Dopamine, DopamineReceptor, Dtetrahydropalmatine, D-tetrahydropalmatine, D-Tetrahydropalmatine, D tetrahydropalmatine, inhibit, Inhibitor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.34% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.63 mM) ; DMSO:25 mg/mL (70.34 mM)

Smiles

[H][C@@]12Cc3ccc (OC) c (OC) c3CN1CCc1cc (OC) c (OC) cc21

Molecular Formula

C21H25NO4

Molecular Weight

355.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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