3-Deoxyaconitine
3-Deoxyaconitine, a derivative of Aconitine, acts as a tetrodotoxin-sensitive sodium channel activator. This induces presynaptic depolarization to block nerve action potentials and inhibit neurotransmitter release, thereby reducing end plate potentials at neuromuscular junctions. It is a research tool for studying ion channel function and synaptic transmission in neuropharmacology.
Product Specifications
CAS Number
3175-95-9
Product Name Alternative
SodiumChannel, Sodium Channel, inhibit, Na channels, Na+ channels, Inhibitor, 3 Deoxyaconitine, 3Deoxyaconitine, 3-Deoxyaconitine
Field of Research
Pharmacology & Drug Discovery
Purity
98.31% (May vary between batches)
Solubility
DMSO:50 mg/mL (79.4 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.18 mM)
Smiles
[H][C@@]12C[C@@]3 (O) [C@H] (OC (=O) c4ccccc4) [C@]1 ([H]) [C@@] (OC (C) =O) (C1[C@H] (OC) [C@@]4 ([H]) C22C1N (CC) C[C@]4 (COC) CC[C@@H]2OC) [C@@H] (O) [C@@H]3OC
Molecular Formula
C34H47NO10
Molecular Weight
629.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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