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Cornuside

Cornuside is a bioactive small molecule with demonstrated immunomodulatory and anti-inflammatory properties. It exerts its effects by inhibiting key pro-inflammatory pathways, including NF-κB and MAPK signaling, and has shown protective potential in research models of cerebral ischemia, myocardial ischemia-reperfusion, and chemical-induced hepatotoxicity both in vitro and in vivo.

Product Specifications

CAS Number

131189-57-6

Product Name Alternative

P38MAPK, p38 MAPK, Inhibitor, inhibit, JNK2, JNK1, NF-κB, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NFkB, NF-kB, ERK1, ERK2, 7-O-Galloylsecologanol, 7-Galloylsecologanol, Cornuside, Comuside

Field of Research

Signal Transduction

Purity

99.57% (May vary between batches)

Solubility

Pyridine, Methanol, etc.:Soluble; Ethanol:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.69 mM) ; DMSO:65 mg/mL (119.82 mM)

Smiles

COC (=O) C1=CO[C@@H] (O[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) [C@H] (C=C) [C@@H]1CCOC (=O) c1cc (O) c (O) c (O) c1

Molecular Formula

C24H30O14

Molecular Weight

542.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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