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Nintedanib esylate

Nintedanib esylate (BIBF 1120 esylate) is a small molecule triple kinase inhibitor targeting VEGFR, FGFR, and PDGFR receptors. It is widely used in preclinical research to study angiogenesis, fibrosis, and oncology in both cellular assays and animal models.

Product Specifications

CAS Number

656247-18-6

Product Name Alternative

Nintedanib, Nintedanib esylate, Nintedanib Ethanesulfonate Salt, PDGFRβ, PDGFRα, PDGFR, FGFR, FGFR1, FGFR2, FGFR3, esylate, BIBF 1120 (esylate), BIBF1120, BIBF-1120, VEGFR3, VEGFR2, VEGFR1, VEGFR

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.43% (May vary between batches)

Solubility

DMSO:101 mg/mL (155.44 mM)

Smiles

CCS (O) (=O) =O.COC (=O) c1ccc2c (NC (=O) \C2=C (/Nc2ccc (cc2) N (C) C (=O) CN2CCN (C) CC2) c2ccccc2) c1

Molecular Formula

C31H33N5O4.C2H6O3S

Molecular Weight

649.76

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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