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VLX1570

VLX1570 is a potent competitive inhibitor of proteasome-associated deubiquitinase (DUB) activity, exhibiting IC50 values between 4.2 and 8.6 μM, with particular potency against USP14. This small molecule is a valuable research tool for studying proteasome function, protein degradation pathways, and cellular homeostasis in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1431280-51-1

Product Name Alternative

Inhibit, Inhibitor, Deubiquitinase, DUBs, DUB, VLX 1570, VLX1570, VLX-1570

Field of Research

Cell Biology, Molecular Biology, Protein Biochemistry

Purity

98.53% (May vary between batches)

Solubility

DMSO:32 mg/mL (68.17 mM)

Smiles

[O-][N+] (=O) c1cc (\C=C2\CCN (C\C (=C\c3ccc (F) c (c3) [N+] ([O-]) =O) C2=O) C (=O) C=C) ccc1F

Molecular Formula

C23H17F2N3O6

Molecular Weight

469.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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