VLX1570
VLX1570 is a potent competitive inhibitor of proteasome-associated deubiquitinase (DUB) activity, exhibiting IC50 values between 4.2 and 8.6 μM, with particular potency against USP14. This small molecule is a valuable research tool for studying proteasome function, protein degradation pathways, and cellular homeostasis in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1431280-51-1
Product Name Alternative
Inhibit, Inhibitor, Deubiquitinase, DUBs, DUB, VLX 1570, VLX1570, VLX-1570
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.53% (May vary between batches)
Solubility
DMSO:32 mg/mL (68.17 mM)
Smiles
[O-][N+] (=O) c1cc (\C=C2\CCN (C\C (=C\c3ccc (F) c (c3) [N+] ([O-]) =O) C2=O) C (=O) C=C) ccc1F
Molecular Formula
C23H17F2N3O6
Molecular Weight
469.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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