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Tiazofurin

Tiazofurin (NSC-286193) is a synthetic nucleoside analog with antineoplastic properties. It functions as a prodrug, being metabolized intracellularly to TAD, a potent inhibitor of IMP dehydrogenase (IMPDH) . This mechanism has been investigated in vitro and in vivo for its effects on cancer cell proliferation and tumor growth.

Product Specifications

CAS Number

60084-10-8

Product Name Alternative

Inhibit, NSC 286193, IMPDH, NSC286193, NSC-286193, Orthopoxvirus, Nucleoside Antimetabolite/Analog, Inhibitor, Riboxamide, Tiazofurin

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Purity

99.28% (May vary between batches)

Solubility

DMSO:50 mg/mL (192.11 mM)

Smiles

NC (=O) c1csc (n1) [C@@H]1O[C@H] (CO) [C@@H] (O) [C@H]1O

Molecular Formula

C9H12N2O5S

Molecular Weight

260.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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