Sulfatinib
Sulfatinib (KDR-IN-1, HMPL-012) is a highly selective small molecule inhibitor targeting VEGFR1/2/3, FGFR1, and CSF1R with potent activity in the low nanomolar range. It is a valuable research tool for investigating angiogenesis, tumor microenvironment, and related signaling pathways in both cellular and animal models of cancer and inflammatory diseases.
Product Specifications
CAS Number
1308672-74-3
Product Name Alternative
KDR-IN-1, KDR, FGFR1, hERG, Sulfatinib
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.93% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.16 mM) ; DMSO:55 mg/mL (114.45 mM)
Smiles
CN (C) CCNS (=O) (=O) Cc1cccc (Nc2nccc (Oc3ccc4[nH]c (C) cc4c3) n2) c1
Molecular Formula
C24H28N6O3S
Molecular Weight
480.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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