PE859
PE859 is a small molecule research compound that potently inhibits the aggregation of both tau protein and amyloid-beta (Aβ) . This dual inhibitory activity makes it a valuable tool for investigating neurodegenerative mechanisms in models of Alzheimer's disease, applicable in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
1402727-29-0
Product Name Alternative
BAmyloid, b Amyloid, Aβ, Beta Amyloid, BetaAmyloid, Inhibitor, Gammasecretase, inhibit, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, β Amyloid, βAmyloid, PE859, PE-859, PE 859, tau
Field of Research
Neuroscience, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.80% (May vary between batches)
Solubility
DMSO:55 mg/mL (122.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM)
Smiles
COc1cc (OCc2ccccn2) ccc1\C=C\c1cc (\C=C\c2ccc3cc[nH]c3c2) [nH]n1
Molecular Formula
C28H24N4O2
Molecular Weight
448.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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