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Temuterkib

Temuterkib (LY3214996) is an oral, potent, and selective ERK1/2 inhibitor with antineoplastic potential. It is used in cancer research, particularly for studying MAPK pathway-driven tumors, and has demonstrated activity in both in vitro cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

1951483-29-6

Product Name Alternative

Inhibit, LY3214996, LY-3214996, LY 3214996, Inhibitor, ERK1, ERK2, ERK, Extracellular signal regulated kinases, Temuterkib

Field of Research

Signal Transduction

Purity

99.37% (May vary between batches)

Solubility

DMSO:7.36 mg/mL (16.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.2 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cn1nccc1Nc1nccc (n1) -c1cc2C (=O) N (CCN3CCOCC3) C (C) (C) c2s1

Molecular Formula

C22H27N7O2S

Molecular Weight

453.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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