Vardenafil hydrochloride trihydrate
Vardenafil hydrochloride trihydrate (BAY38-9456) is a selective PDE5 inhibitor with an IC50 of 0.7 nM, showing high selectivity over PDE1 (IC50=180 nM) . It is widely used in biochemical research to study erectile dysfunction mechanisms and for in vitro phosphodiesterase activity assays.
Product Specifications
CAS Number
330808-88-3
Product Name Alternative
Impotence, muscle, Inhibitor, inhibit, PDE1, hepatitis, Endogenous Metabolite, erectile dysfunction, erectile, diabetes, dysfunction, cGMP, BAY38-9456, smooth, stimulation, selective, PDE5, pharmacokinetics, Phosphodiesterase (PDE), Vardenafil, Vardenafil HCl, Vardenafil HCl Trihydrate, Vardenafil hydrochloride, Vardenafil Hydrochloride, Vardenafil hydrochloride Trihydrate, Vardenafil hydrochloride trihydrate, Zucker diabetic fatty (ZDF) rats
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.66% (May vary between batches)
Solubility
Ethanol:16 mg/mL (27.63 mM) ; H2O:10 mg/mL (17.27 mM) ; DMSO:93 mg/mL (160.59 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.7 mM)
Smiles
O.O.O.Cl.CCCc1nc (C) c2n1nc ([nH]c2=O) -c1cc (ccc1OCC) S (=O) (=O) N1CCN (CC) CC1
Molecular Formula
C23H32N6O4S·HCl·3H2O
Molecular Weight
579.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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