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AS-8351

AS8351 (NSC51355) is a histone demethylase inhibitor. It has been utilized in cellular reprogramming research, notably in combination with other small molecules to convert human fetal lung fibroblasts into cardiomyocyte-like cells in vitro, demonstrating its role in epigenetic regulation and cardiac regeneration studies.

Product Specifications

CAS Number

796-42-9

Product Name Alternative

NSC-51355

Field of Research

Epigenetics & Chromatin, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

KDM5B histone demethylase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 45 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)

Smiles

NN (\C=C1/C (=O) C=Cc2ccccc12) C (=O) c1ccncc1

Molecular Formula

C17H13N3O2

Molecular Weight

291.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone

Available Sizes

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