AS-8351
AS8351 (NSC51355) is a histone demethylase inhibitor. It has been utilized in cellular reprogramming research, notably in combination with other small molecules to convert human fetal lung fibroblasts into cardiomyocyte-like cells in vitro, demonstrating its role in epigenetic regulation and cardiac regeneration studies.
Product Specifications
CAS Number
796-42-9
Product Name Alternative
NSC-51355
Field of Research
Epigenetics & Chromatin, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
KDM5B histone demethylase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 45 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Smiles
NN (\C=C1/C (=O) C=Cc2ccccc12) C (=O) c1ccncc1
Molecular Formula
C17H13N3O2
Molecular Weight
291.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
Available Sizes
Frequently Asked Questions
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