KG5
KG5 is a dual allosteric inhibitor targeting PDGFRβ and B-Raf, with additional activity against FLT3, KIT, and c-Raf. It exhibits anticancer and antiangiogenic properties, making it a useful compound for oncology research in both cellular and animal models of relevant cancers.
Product Specifications
CAS Number
877874-85-6
Product Name Alternative
Cluster of differentiation antigen 135, CD135, CD117, c-Kit, cKit, c-Raf, C-Raf, anticancer, antiangiogenic, B-Raf, KG 5, KG5, KG-5, Kit, KIT, inhibit, metastasis, Platelet-derived growth factor receptor, PDGFR, Inhibitor, Fms like tyrosine kinase 3, FLT3, SCFR, PDGFRβ, PDGFRα, Raf, Raf kinases, phosphorylation
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.20% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (7.18 mM) ; DMSO:95 mg/mL (206.77 mM)
Smiles
CSc1nc (N) cc (Oc2ccc (cc2) -c2nnc (Nc3cccc (c3) C (F) (F) F) [nH]2) n1
Molecular Formula
C20H16F3N7OS
Molecular Weight
459.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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