AFN-1252
AFN-1252 (Debio 1452) is a potent FabI enoyl-ACP reductase inhibitor active against clinical isolates of Staphylococcus aureus and S. epidermidis (MIC ≤0.12 μg/ml) . It serves as a valuable research tool for studying bacterial fatty acid biosynthesis and has demonstrated efficacy in preclinical models of staphylococcal infection.
Product Specifications
CAS Number
620175-39-5
Product Name Alternative
AFN 1252, AFN1252, AFN-1252, API1252, API-1252, API 1252, Antibiotic, Bacterial, inhibit, Inhibitor, enoyl-acyl carrier protein reductase (FabI), Debio 1452, Debio1452, Debio-1452
Field of Research
Infectious Disease & Virology
Purity
98.71% (May vary between batches)
Solubility
DMSO:5.8 mg/mL (15.45 mM)
Smiles
CN (Cc1oc2ccccc2c1C) C (=O) \C=C\C1=CNC2=NC (=O) CCC2=C1
Molecular Formula
C22H21N3O3
Molecular Weight
375.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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