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Itaconate-alkyne

ITalk is a bioorthogonal itaconate-alkyne probe enabling site-specific chemoproteomic profiling of this immunometabolite. It facilitates the identification and biochemical validation of direct protein targets in both in vitro and in vivo models of macrophage inflammation.

Product Specifications

CAS Number

2454181-83-8

Product Name Alternative

Probe, site-specific, Raw264.7, quantitative, DDB1, chemoproteomic, bioorthogonal, antiinflammatory, ACLY, AK2, ITalk, Itaconate, Itaconate alkyne, Itaconatealkyne, Itaconate-alkyne, Itaconation, IL-1β, NRF-2, inhibit, LPS, Inhibitor, labeling, GSN

Purity

99.17% (May vary between batches)

Solubility

DMSO:245 mg/mL (1028.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.98 mM)

Smiles

C (CC (C (O) =O) =C) (OCCCCCCC#C) =O

Molecular Formula

C13H18O4

Molecular Weight

238.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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