Itaconate-alkyne
ITalk is a bioorthogonal itaconate-alkyne probe enabling site-specific chemoproteomic profiling of this immunometabolite. It facilitates the identification and biochemical validation of direct protein targets in both in vitro and in vivo models of macrophage inflammation.
Product Specifications
CAS Number
2454181-83-8
Product Name Alternative
Probe, site-specific, Raw264.7, quantitative, DDB1, chemoproteomic, bioorthogonal, antiinflammatory, ACLY, AK2, ITalk, Itaconate, Itaconate alkyne, Itaconatealkyne, Itaconate-alkyne, Itaconation, IL-1β, NRF-2, inhibit, LPS, Inhibitor, labeling, GSN
Purity
99.17% (May vary between batches)
Solubility
DMSO:245 mg/mL (1028.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.98 mM)
Smiles
C (CC (C (O) =O) =C) (OCCCCCCC#C) =O
Molecular Formula
C13H18O4
Molecular Weight
238.28
Storage Conditions
-20°C
Notes
For research use only.
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