BPTU
BPTU (BMS-646786) is a potent, non-nucleotide allosteric P2Y1 receptor antagonist (EC50 0.06-0.3 μM) that binds outside the helical bundle. It has demonstrated antithrombotic effects by inhibiting platelet aggregation and has been used in vitro and in vivo to study colon motility and purinergic signaling.
Product Specifications
CAS Number
870544-59-5
Product Name Alternative
Thrombosis, inhibit, P2YReceptor, P2Y1, P2Y Receptor, P2Y, Inhibitor, antithrombotic, BPTU, BMS646786, BMS-646786, BMS 646786
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.37% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.49 mM) ; DMSO:35.71 mg/mL (80.17 mM)
Smiles
CC (C) (C) c1ccccc1Oc1ncccc1NC (=O) Nc1ccc (OC (F) (F) F) cc1
Molecular Formula
C23H22F3N3O3
Molecular Weight
445.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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