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IRAK4-IN-1

IRAK4-IN-1 is a potent and selective small molecule inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4), exhibiting an IC50 value of 7 nM. It serves as a valuable research tool for investigating IRAK4-mediated signaling in innate immunity and inflammation, applicable in both cellular and biochemical assay systems.

Product Specifications

CAS Number

1820787-94-7

Product Name Alternative

Inhibit, Interleukin-1 receptor associated kinase, IL-1R associated kinase, IRAK, IRAK-4, IRAK4 IN 1, IRAK4IN1, IRAK-4-IN-1, IRAK4-IN-1, Inhibitor

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

98.18% (May vary between batches)

Solubility

H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.96 mM) ; DMSO:1 mg/mL (2.96 mM)

Smiles

N#Cc1ccc2ncnc (N[C@H]3CC[C@@H] (CC3) N3CCOCC3) c2c1

Molecular Formula

C19H23N5O

Molecular Weight

337.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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