Avibactam sodium
Avibactam sodium (NXL-104) is a reversible covalent inhibitor of β-lactamases, including TEM-1, P99, and KPC-2, with IC50 values of 8, 80, and 38 nM, respectively. It exhibits antimicrobial activity and is utilized in research models of urinary tract infections, both in vitro and in vivo.
Product Specifications
CAS Number
1192491-61-4
Product Name Alternative
Pseudomonas aeruginosa, TEM-1, TEM-1 β-lactamases, β-lactamase, KPC-2 β-lactamases, Klebsiella pneumonia, P99 β-lactamases, inhibit, NXL 104, NXL104, NXL-104, Inhibitor, AVE-1330A, Avibactam, Avibactam sodium, Bacterial, antibacterial, Antibiotic, CTX-M-15
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.16% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.41 mM) ; DMSO:257 mg/mL (894.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:52 mg/mL (181.05 mM)
Smiles
[Na+].NC (=O) [C@@H]1CC[C@@H]2CN1C (=O) N2OS ([O-]) (=O) =O
Molecular Formula
C7H10N3NaO6S
Molecular Weight
287.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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