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Avibactam sodium

Avibactam sodium (NXL-104) is a reversible covalent inhibitor of β-lactamases, including TEM-1, P99, and KPC-2, with IC50 values of 8, 80, and 38 nM, respectively. It exhibits antimicrobial activity and is utilized in research models of urinary tract infections, both in vitro and in vivo.

Product Specifications

CAS Number

1192491-61-4

Product Name Alternative

Pseudomonas aeruginosa, TEM-1, TEM-1 β-lactamases, β-lactamase, KPC-2 β-lactamases, Klebsiella pneumonia, P99 β-lactamases, inhibit, NXL 104, NXL104, NXL-104, Inhibitor, AVE-1330A, Avibactam, Avibactam sodium, Bacterial, antibacterial, Antibiotic, CTX-M-15

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

99.16% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.41 mM) ; DMSO:257 mg/mL (894.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:52 mg/mL (181.05 mM)

Smiles

[Na+].NC (=O) [C@@H]1CC[C@@H]2CN1C (=O) N2OS ([O-]) (=O) =O

Molecular Formula

C7H10N3NaO6S

Molecular Weight

287.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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