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SAG hydrochloride (912545-86-9 (free base) )

SAG hydrochloride (CAS 912545-86-9 for the free base) is a potent and cell-permeable Smoothened (SMO) receptor agonist. It is widely used in research to activate the Hedgehog signaling pathway for both in vitro cellular studies and in vivo developmental biology experiments.

Product Specifications

CAS Number

2095432-58-7

Product Name Alternative

Hedgehog/Smoothened, Hedgehog, Smoothened Agonist HCl, Smoothened, SAG hydrochloride (912545 86 9 (free base) ), SAG hydrochloride (912545869 (free base) ), SAG hydrochloride (912545-86-9 (free base) )

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.8 mM) ; DMSO:66 mg/mL (125.35 mM) ; Ethanol:38 mg/mL (72.17 mM)

Smiles

Cl.CN[C@H]1CC[C@@H] (CC1) N (Cc1cccc (c1) -c1ccncc1) C (=O) c1sc2ccccc2c1Cl

Molecular Formula

C28H29Cl2N3OS

Molecular Weight

526.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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