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XMU-MP-1

XMU-MP-1 is a potent, reversible, and selective inhibitor of the kinases MST1 and MST2, with IC50 values of 71.1 nM and 38.1 nM, respectively. This small molecule is a valuable research tool for studying the Hippo signaling pathway in both cellular and in vivo models of tissue regeneration and cancer.

Product Specifications

CAS Number

2061980-01-4

Product Name Alternative

MST2, MST1, inhibit, Inhibitor, Hippopathway, Hippo (MST), Hippo pathway, XMU MP 1, XMUMP1, XMU-MP-1

Field of Research

Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 15 mg/ml)

Smiles

CN1c2ccsc2C (=O) N (C) c2cnc (Nc3ccc (cc3) S (N) (=O) =O) nc12

Molecular Formula

C17H16N6O3S2

Molecular Weight

416.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

4-[ (6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e]diazepin-2-yl) amino]benzenesulfonamide

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