NCT-503
NCT-503 is a selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 μM) with demonstrated antitumor activity. It is used in cancer metabolism research to suppress the growth of PHGDH-dependent tumors in both cellular and animal models.
Product Specifications
CAS Number
1916571-90-8
Product Name Alternative
PHGDH (Cell-free), TAMReceptor, TAM Receptor, Inhibitor, FLT3, NCT 503, NCT503, NCT-503, inhibit, AXL
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Purity
98.91% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1.83 mg/mL (4.48 mM) ; Ethanol:75 mg/mL (183.61 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:127 mg/mL (310.91 mM)
Smiles
Cc1cc (C) nc (NC (=S) N2CCN (Cc3ccc (cc3) C (F) (F) F) CC2) c1
Molecular Formula
C20H23F3N4S
Molecular Weight
408.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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