PF-3758309 hydrochloride
PF-3758309 hydrochloride is an orally bioavailable small-molecule inhibitor targeting p21-activated kinase 4 (PAK4), which is frequently overexpressed in cancers. Its inhibition of PAK4 activity disrupts cancer cell proliferation and survival, demonstrating antitumor effects in both cellular assays and in vivo xenograft models across various cancer types.
Product Specifications
CAS Number
1279034-84-2
Product Name Alternative
ATP-competitive, Apoptosis, oncogenic, PAK, PAK3, PAK1, PAK4, PAK5, PAK6, inhibit, Inhibitor, growth, signaling, PF 03758309 Hydrochloride, PF 03758309, PF 3758309, PF 3758309 Hydrochloride, PF 3758309 hydrochloride, PF3758309, PF-3758309, PF3758309 hydrochloride, PF3758309 Hydrochloride, PF-3758309 Hydrochloride, PF-03758309, PF03758309 Hydrochloride, PF-03758309 hydrochloride, PF-03758309 Hydrochloride, PF03758309, p21 activated kinases, proliferation, survival, tumor
Field of Research
Cell Biology, Signal Transduction
Purity
98.11% (May vary between batches)
Solubility
DMSO:45 mg/mL (85.38 mM)
Smiles
Cl.CN (C) C[C@@H] (NC (=O) N1Cc2c (Nc3nc (C) nc4ccsc34) n[nH]c2C1 (C) C) c1ccccc1
Molecular Formula
C25H31ClN8OS
Molecular Weight
527.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15158310 1 Vial
Lentiviral human PTGIR shRNA (UAS) - Lentiviral human PTGIR shRNA (UAS) (100)
Sign In for Pricing
View Details