Rubiadin-1-methyl ether
Rubiadin-1-methyl ether is a natural compound that suppresses osteoclast-mediated bone resorption. It functions by inhibiting NF-κB pathway activation, specifically blocking p65 phosphorylation, IκBα degradation, and p65 nuclear translocation. This mechanism supports its research application in studying bone metabolism disorders such as osteoporosis in cellular models.
Product Specifications
CAS Number
7460-43-7
Product Name Alternative
Rubiadin 1 methyl ether, Rubiadin 1-methyl ether, Rubiadin1methyl ether, Rubiadin-1-methyl ether, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NF-kB, NFkB, NF-κB, inhibit, Inhibitor, Antifection, Anti-infection, Antiinfection
Field of Research
Infectious Disease & Virology, Signal Transduction
Purity
97.79% (May vary between batches)
Solubility
DMSO:2.69 mg/mL (10.03 mM)
Smiles
COc1c (C) c (O) cc2C (=O) c3ccccc3C (=O) c12
Molecular Formula
C16H12O4
Molecular Weight
268.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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