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I-CBP112 hydrochloride

I-CBP112 is a potent and selective small molecule inhibitor of the CBP/p300 bromodomains. It reduces the leukemia-initiating potential of MLL-AF9+ AML cells in vitro and in vivo and shows synergistic effects with BET inhibitors like JQ1 and chemotherapeutics such as doxorubicin in oncology research.

Product Specifications

CAS Number

2147701-33-3

Product Name Alternative

CBP/p300, Leukemia cell, CBP/p300, Prostate cancer cell, Inhibitor, I-CBP 112 Hydrochloride, I-CBP112, ICBP112 hydrochloride, I-CBP112 Hydrochloride, I-CBP-112 hydrochloride, I-CBP-112 Hydrochloride, I CBP112 hydrochloride, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit

Field of Research

Epigenetics & Chromatin

Purity

97.98% (May vary between batches)

Solubility

DMSO:60 mg/mL (118.8 mM)

Smiles

O (C[C@@H]1CN (C) CCC1) C2=C3C (=CC (=C2) C4=CC (OC) =C (OC) C=C4) CN (C (CC) =O) CCO3.Cl

Molecular Formula

C27H37ClN2O5

Molecular Weight

505.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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