AZD3759 hydrochloride
AZD3759 hydrochloride is a brain-penetrant, orally bioavailable EGFR inhibitor with potent activity against mutant forms, including L858R and exon 19 deletion, as well as wild-type EGFR. It is a valuable research tool for investigating EGFR-driven cancers, particularly in models of brain metastasis, in both in vitro and in vivo studies.
Product Specifications
CAS Number
1626387-81-2
Product Name Alternative
AZD3759 hydrochloride, AZD3759 Hydrochloride, AZD-3759 hydrochloride, AZD-3759 Hydrochloride, AZD 3759 Hydrochloride, EGFR (exon 19De), EGFR (L858R), EGFR (wt)
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.41% (May vary between batches)
Solubility
DMSO:50 mg/mL (100.73 mM)
Smiles
C[C@@H]1CN (CCN1C (=O) OC2=C (C=C3C (=C2) C (=NC=N3) NC4=C (C (=CC=C4) Cl) F) OC) C.Cl
Molecular Formula
C22H24Cl2FN5O3
Molecular Weight
496.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal ABCE1 Antibody [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NB400-116AF532 0.1 mL
Rabbit Polyclonal ABCE1 Antibody [Alexa Fluor 532]
Sign In for Pricing
View Details 
PA2185-HRP 100 µg/Vial
Anti-EAAT1/SLC1A3 Antibody Picoband®, HRP Conjugate
Sign In for Pricing
View Details 
MBS1386707-01 0.05 mg (E-Coli)
Recombinant Kluyveromyces lactis Topoisomerase I damage affected protein 11 (TDA11)
Sign In for Pricing
View Details MBS1386707-02 0.05 mg (Yeast)
Recombinant Kluyveromyces lactis Topoisomerase I damage affected protein 11 (TDA11)
Sign In for Pricing
View Details MBS1386707-03 0.05 mg (Baculovirus)
Recombinant Kluyveromyces lactis Topoisomerase I damage affected protein 11 (TDA11)
Sign In for Pricing
View Details