GLPG0187
GLPG0187 is a potent broad-spectrum integrin antagonist with an IC50 of 1.3 nM against αvβ1-integrin. This small molecule inhibitor is a valuable research tool for studying integrin function in fibrosis, cancer, and angiogenesis, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1320346-97-1
Product Name Alternative
GLPG 0187, GLPG0187, GLPG-0187, Inhibitor, Integrin, inhibit, αvβ1 integrin
Field of Research
Signal Transduction
Purity
99.01% (May vary between batches)
Solubility
DMSO:13.38 mg/mL (22.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.68 mM)
Smiles
COc1ccc (cc1) S (=O) (=O) N[C@@H] (CNc1nc (C) nc (N2CCC (CC2) C2=CC=C3CCCN=C3N2) c1C) C (O) =O
Molecular Formula
C29H37N7O5S
Molecular Weight
595.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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