BAY 61-3606
BAY 61-3606 is a potent, selective, and reversible ATP-competitive inhibitor of spleen tyrosine kinase (Syk) with a Ki of 7.5 nM. It is widely used in vitro and in vivo to investigate Syk's role in immunoreceptor signaling, autoimmune disorders, and hematological malignancies, demonstrating high selectivity over related kinases like Src and Lyn.
Product Specifications
CAS Number
732983-37-8
Product Name Alternative
Inhibitor, inhibit, BAY 61 3606, BAY 613606, BAY 61-3606, Apoptosis, Spleen tyrosine kinase, Syk, Syk inhibitor IV
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.72% (May vary between batches)
Solubility
DMSO:3.91 mg/mL (10.02 mM)
Smiles
N (C=1N2C (C=C (N1) C3=CC (OC) =C (OC) C=C3) =NC=C2) C4=C (C (N) =O) C=CC=N4
Molecular Formula
C20H18N6O3
Molecular Weight
390.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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