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ARN-3236

ARN-3236 is a potent, orally bioavailable, and selective salt-inducible kinase 2 (SIK2) inhibitor, with IC50 values of <1 nM, 21.63 nM, and 6.63 nM for SIK2, SIK1, and SIK3, respectively. This small molecule exhibits anti-cancer activity and is a valuable research tool for studying SIK2 signaling in both in vitro cellular assays and in vivo cancer models.

Product Specifications

CAS Number

1613710-01-2

Product Name Alternative

ARN3236, ARN-3236, ARN 3236, inhibit, Inhibitor, Salt-inducible Kinase (SIK), SIK2

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

98.89% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.89 mM) ; DMSO:130 mg/mL (386.43 mM)

Smiles

COc1ccc (-c2c[nH]c3nccc (-c4ccsc4) c23) c (OC) c1

Molecular Formula

C19H16N2O2S

Molecular Weight

336.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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