ARN-3236
ARN-3236 is a potent, orally bioavailable, and selective salt-inducible kinase 2 (SIK2) inhibitor, with IC50 values of <1 nM, 21.63 nM, and 6.63 nM for SIK2, SIK1, and SIK3, respectively. This small molecule exhibits anti-cancer activity and is a valuable research tool for studying SIK2 signaling in both in vitro cellular assays and in vivo cancer models.
Product Specifications
CAS Number
1613710-01-2
Product Name Alternative
ARN3236, ARN-3236, ARN 3236, inhibit, Inhibitor, Salt-inducible Kinase (SIK), SIK2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.89 mM) ; DMSO:130 mg/mL (386.43 mM)
Smiles
COc1ccc (-c2c[nH]c3nccc (-c4ccsc4) c23) c (OC) c1
Molecular Formula
C19H16N2O2S
Molecular Weight
336.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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