Chelidonine
Chelidonine, a bioactive alkaloid from Chelidonium majus, induces apoptosis in cancer cells like HeLa via p38/p53 and PI3K/AKT pathways and shows promise in overcoming multidrug resistance. It also exhibits anti-metastatic potential by inhibiting integrin signaling in invasive breast cancer cells, as demonstrated in vitro.
Product Specifications
CAS Number
476-32-4
Product Name Alternative
Stylophorin, Helidonine, melanoma cell, Khelidonin, isoquinoline alkaloid, InfluenzaVirus, Influenza Virus, Apoptosis, anticancer, A-375, Dugesia japonica, Chelidonine
Field of Research
Cell Biology, Infectious Disease & Virology
Purity
98.00% (May vary between batches)
Solubility
DMSO:5 mg/mL (14.15 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.83 mM)
Smiles
[H][C@]12[C@@H] (O) Cc3cc4OCOc4cc3[C@@]1 ([H]) N (C) Cc1c3OCOc3ccc21
Molecular Formula
C20H19NO5
Molecular Weight
353.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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