Thevetiaflavone
Thevetiaflavone could upregulate the expression of Bcl-2 and downregulate that of Bax and caspase-3.
Product Specifications
CAS Number
[29376-68-9]
Product Name Alternative
Apigenin-5-methyl ether
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Bcl-2 Family; Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Thevetiaflavone.html
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=CC(OC)=C13
Molecular Formula
C16H12O5
Molecular Weight
284.26
Precautions
H315, H319, H335
References & Citations
[1]Yao H, et al. Thevetiaflavone from Wikstroemia indica ameliorates PC12 cells injury induced by OGD/R via improving ROS-mediated mitochondrial dysfunction. Mol Med Rep. 2017 Dec;16 (6) :9197-9202.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2; Caspase 3
Available Sizes
Curated Selection
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