Atractylenolide I
Atractylenolide-I exhibits anti-inflammatory properties by suppressing TNF-α and IL-6 production, ameliorating sepsis-related organ dysfunction. It also enhances paclitaxel sensitivity in MyD88 (+) cancer cells via inhibition of the TLR4/MyD88 pathway, making it a compound of interest for inflammation and oncology research in both cellular and animal models.
Product Specifications
CAS Number
73069-13-3
Product Name Alternative
TLR, Toll-like Receptor (TLR), TNF-α, STAT, Atractylenolide I, JAK, Janus kinase, inhibit, Inhibitor, ILReceptor, IL-6, IL Receptor
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.00 mg/mL (8.68 mM) ; DMSO:55.00 mg/mL (238.82 mM)
Smiles
CC1=C2C[C@H]3C (=C) CCC[C@]3 (C) C=C2OC1=O
Molecular Formula
C15H18O2
Molecular Weight
230.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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