Corynoxine
Corynoxine is a tetracyclic oxindole alkaloid derived from Uncaria macrophylla. It functions as an autophagy enhancer, facilitating the clearance of α-synuclein via Akt/mTOR pathway inhibition, making it a useful research tool for studying neurodegenerative mechanisms in cellular models.
Product Specifications
CAS Number
6877-32-3
Product Name Alternative
Corynoxine, Autophagy, alkaloid, inhibit, mTOR, macrophylla, Inhibitor, synuclein Akt, oxindole, Uncaria, tetracyclic
Field of Research
Cell Biology
Purity
96.83% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM) ; DMSO:55 mg/mL (143.05 mM) ; Ethanol:50 mg/mL (130.05 mM) ; H2O:Insoluble
Smiles
CC[C@@H]1CN2CC[C@]3 ([C@@H]2C[C@@H]1\C (=C/OC) C (=O) OC) C (=O) Nc1ccccc31
Molecular Formula
C22H28N2O4
Molecular Weight
384.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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