Desmethoxyyangonin
Desmethoxyyangonin (5,6-Dehydrokavain) demonstrates hepatoprotective effects against LPS or LPS/D-GalN-induced injury in cellular and animal models by modulating IKK/NFκB and Jak2/STAT3 pathways. It also induces CYP3A23 expression, potentially via PXR-independent mechanisms, making it a useful research tool for studying inflammation and drug metabolism.
Product Specifications
CAS Number
15345-89-8
Product Name Alternative
Desmethoxyyangonin, Desmethoxy yangonin, Demethoxyyangonin, 5,6-Dehydrokavain, Inhibitor, MAO, Monoamine Oxidase, MonoamineOxidase, inhibit
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.29% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (8.76 mM) ; DMSO:45 mg/mL (197.16 mM)
Smiles
COc1cc (\C=C\c2ccccc2) oc (=O) c1
Molecular Formula
C14H12O3
Molecular Weight
228.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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