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Columbamine

Columbamine is a bioactive small molecule with an IC50 of 48.1 μM, demonstrating potent anti-proliferative and anti-vasculogenic activity against metastatic human osteosarcoma U2OS cells in vitro. Its efficacy against cancer cell lines with low cytotoxicity makes it a candidate for oncology research, particularly in studying metastasis and angiogenesis.

Product Specifications

CAS Number

3621-36-1

Product Name Alternative

Inhibitor, inhibit, Dehydroisocorypalmine, Columbamin, Columbamine

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research

Purity

99.16% (May vary between batches)

Solubility

DMSO:3.39 mg/mL (10.02 mM)

Smiles

OC=1C=C2C=3[N+] (=CC=4C (C3) =CC=C (OC) C4OC) CCC2=CC1OC

Molecular Formula

C20H20NO4

Molecular Weight

338.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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