Columbamine
Columbamine is a bioactive small molecule with an IC50 of 48.1 μM, demonstrating potent anti-proliferative and anti-vasculogenic activity against metastatic human osteosarcoma U2OS cells in vitro. Its efficacy against cancer cell lines with low cytotoxicity makes it a candidate for oncology research, particularly in studying metastasis and angiogenesis.
Product Specifications
CAS Number
3621-36-1
Product Name Alternative
Inhibitor, inhibit, Dehydroisocorypalmine, Columbamin, Columbamine
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research
Purity
99.16% (May vary between batches)
Solubility
DMSO:3.39 mg/mL (10.02 mM)
Smiles
OC=1C=C2C=3[N+] (=CC=4C (C3) =CC=C (OC) C4OC) CCC2=CC1OC
Molecular Formula
C20H20NO4
Molecular Weight
338.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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