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N-Methylcytisine

N-Methylcytisine (Caulophylline) exhibits high affinity (KD = 5 nM) for nicotinic acetylcholine receptors (nAChRs) from squid optical ganglia. Unlike its derivatives, cytisine effectively inhibits 14C-tubocurarine binding (Ki=7 nM) . This compound is a valuable research tool for studying nAChR pharmacology and ligand interactions in neurobiological in vitro assays.

Product Specifications

CAS Number

486-86-2

Product Name Alternative

Inhibitor, N Methylcytisine, inhibit, nAChR, Nicotinic acetylcholine receptors, NMethylcytisine, N-Methylcytisine, Caulophylline

Field of Research

Neuroscience

Purity

99.62% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.79 mM) ; DMSO:27.5 mg/mL (134.63 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Smiles

CN1C[C@@H]2C[C@H] (C1) c1cccc (=O) n1C2

Molecular Formula

C12H16N2O

Molecular Weight

204.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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