N-Methylcytisine
N-Methylcytisine (Caulophylline) exhibits high affinity (KD = 5 nM) for nicotinic acetylcholine receptors (nAChRs) from squid optical ganglia. Unlike its derivatives, cytisine effectively inhibits 14C-tubocurarine binding (Ki=7 nM) . This compound is a valuable research tool for studying nAChR pharmacology and ligand interactions in neurobiological in vitro assays.
Product Specifications
CAS Number
486-86-2
Product Name Alternative
Inhibitor, N Methylcytisine, inhibit, nAChR, Nicotinic acetylcholine receptors, NMethylcytisine, N-Methylcytisine, Caulophylline
Field of Research
Neuroscience
Purity
99.62% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.79 mM) ; DMSO:27.5 mg/mL (134.63 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Smiles
CN1C[C@@H]2C[C@H] (C1) c1cccc (=O) n1C2
Molecular Formula
C12H16N2O
Molecular Weight
204.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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