YS-370
YS-370 is an orally bioavailable small molecule that inhibits P-glycoprotein (P-gp) and moderately inhibits CYP3A4. It reverses multidrug resistance to agents like paclitaxel and colchicine in vitro and demonstrates enhanced antitumor efficacy in combination with paclitaxel in vivo.
Product Specifications
CAS Number
2470908-79-1
Product Name Alternative
YS370, YS-370, YS 370, P-gp, Pgp
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.50% (May vary between batches)
Solubility
DMSO:6 mg/mL (9.04 mM)
Smiles
COc1cc2ncnc (-c3c (-c4ccccc4) n (Cc4ccccc4Br) c4ccccc34) c2cc1OCCCN1CCOCC1
Molecular Formula
C37H35BrN4O3
Molecular Weight
663.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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