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YS-370

YS-370 is an orally bioavailable small molecule that inhibits P-glycoprotein (P-gp) and moderately inhibits CYP3A4. It reverses multidrug resistance to agents like paclitaxel and colchicine in vitro and demonstrates enhanced antitumor efficacy in combination with paclitaxel in vivo.

Product Specifications

CAS Number

2470908-79-1

Product Name Alternative

YS370, YS-370, YS 370, P-gp, Pgp

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

97.50% (May vary between batches)

Solubility

DMSO:6 mg/mL (9.04 mM)

Smiles

COc1cc2ncnc (-c3c (-c4ccccc4) n (Cc4ccccc4Br) c4ccccc34) c2cc1OCCCN1CCOCC1

Molecular Formula

C37H35BrN4O3

Molecular Weight

663.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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