NRX-1933
NRX-1933 is a molecular glue degrader that stabilizes the interaction between oncogenic β-Catenin and the SCFβ-TrCP E3 ligase, promoting β-Catenin's ubiquitination and degradation. This tool compound is used in vitro and in vivo to study Wnt/β-catenin signaling in cancer and regenerative biology research.
Product Specifications
CAS Number
2763260-30-4
Product Name Alternative
Inhibitor, NRX 1933, NRX1933, NRX-1933, inhibit
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (9.42 mM) ; DMSO:80 mg/mL (228.4 mM)
Smiles
FC (F) (F) c1ccc (C (=O) Nc2cccc (c2) -c2nn[nH]n2) c (=O) [nH]1
Molecular Formula
C14H9F3N6O2
Molecular Weight
350.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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