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NRX-1933

NRX-1933 is a molecular glue degrader that stabilizes the interaction between oncogenic β-Catenin and the SCFβ-TrCP E3 ligase, promoting β-Catenin's ubiquitination and degradation. This tool compound is used in vitro and in vivo to study Wnt/β-catenin signaling in cancer and regenerative biology research.

Product Specifications

CAS Number

2763260-30-4

Product Name Alternative

Inhibitor, NRX 1933, NRX1933, NRX-1933, inhibit

Field of Research

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.79% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (9.42 mM) ; DMSO:80 mg/mL (228.4 mM)

Smiles

FC (F) (F) c1ccc (C (=O) Nc2cccc (c2) -c2nn[nH]n2) c (=O) [nH]1

Molecular Formula

C14H9F3N6O2

Molecular Weight

350.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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