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DPTIP

DPTIP is a potent and selective inhibitor of neutral sphingomyelinase 2 (nSMase2), exhibiting an IC50 of 30 nM. This small molecule is a valuable research tool for investigating the role of nSMase2 in ceramide-mediated pathways, including studies of apoptosis, neuroinflammation, and exosome biology in cellular and animal models.

Product Specifications

CAS Number

351353-48-5

Product Name Alternative

Extracellular, exosome, Inhibitor, inhibit, N-SMase, neutral sphingomyelinase, DPTIP, Phospholipase, vesicles

Field of Research

Metabolism Research

Purity

98.80% (May vary between batches)

Solubility

DMSO:27 mg/mL (71.35 mM)

Smiles

COc1cc (cc (OC) c1O) -c1nc (c ([nH]1) -c1cccs1) -c1ccccc1

Molecular Formula

C21H18N2O3S

Molecular Weight

378.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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