HIF-2α-IN-4
HIF-2α-IN-4 is a potent small molecule inhibitor of HIF-2α protein synthesis, with an IC50 of 5 μM, targeting the 5'UTR iron response element for oxygen sensing. It effectively suppresses both constitutive and hypoxia-induced HIF-2α expression, making it a valuable tool for studying HIF-2α biology in cancer and renal disease models in vitro.
Product Specifications
CAS Number
882268-69-1
Product Name Alternative
Iron-responsive, inhibit, oxygen sensing, HIF, HIF 2α IN 4, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIF-2a-IN-4, HIF-2α, HIF2αIN4, HIF-2α-IN-4, HIF-2alpha-IN-4, HIF-PH, HIFProlylHydroxylase, HIFs, Inhibitor, hypoxia, Hypoxia-inducible factors, translation
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
≥98% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (58.02 mM)
Smiles
COC (=O) c1sccc1N\N=C (/C#N) S (C) (=O) =O
Molecular Formula
C9H9N3O4S2
Molecular Weight
287.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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