Iguratimod
Iguratimod (T-614) is a selective COX-2 inhibitor (IC50 = 20 μM) and macrophage migration inhibitory factor (MIF) antagonist (IC50 = 6.81 μM) . This small molecule is a research tool for studying rheumatoid arthritis mechanisms and has demonstrated anti-inflammatory and immunomodulatory effects in both cellular and animal models of disease.
Product Specifications
CAS Number
123663-49-0
Product Name Alternative
Iguratimod, MIF, inhibit, Inhibitor, Cyclooxygenase, COX-2, COX, T614, T-614, T 614
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.75% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.71 mM)
Smiles
O=C1C=2C (=CC (NS (C) (=O) =O) =C (OC3=CC=CC=C3) C2) OC=C1NC=O
Molecular Formula
C17H14N2O6S
Molecular Weight
374.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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