SSR240612
SSR240612 is a potent, orally bioavailable non-peptide antagonist that selectively targets the bradykinin B1 receptor, demonstrating high affinity (Ki = 0.48-0.73 nM) and excellent selectivity over the B2 receptor. It is a valuable research tool for investigating the role of the B1 receptor in pain, inflammation, and neuropathic conditions in both in vitro and in vivo models.
Product Specifications
CAS Number
464930-42-5
Product Name Alternative
SSR 240612, SSR240612, SSR-240612, Inhibitor, inhibit, B1 Receptor, BradykininReceptor, Bradykinin Receptor
Field of Research
Pharmacology & Drug Discovery
Purity
98.59% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.04 mM) ; DMSO:100 mg/mL (126.04 mM)
Smiles
Cl.COc1ccc2cc (ccc2c1) S (=O) (=O) N[C@H] (CC (=O) N[C@H] (Cc1ccc (CN2[C@@H] (C) CCC[C@H]2C) cc1) C (=O) N (C) C (C) C) c1ccc2OCOc2c1
Molecular Formula
C42H53ClN4O7S
Molecular Weight
793.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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