Pamiparib
Pamiparib (BGB-290) is a potent, brain-penetrant, and selective PARP1/2 inhibitor with strong PARP-trapping activity. It is widely used in preclinical cancer research, demonstrating efficacy in both in vitro assays and in vivo models for solid tumors, including those with central nervous system involvement.
Product Specifications
CAS Number
1446261-44-4
Product Name Alternative
BGB290, BGB-290, BGB 290, Inhibitor, inhibit, Pamiparib, PARP, PARP1, PARP2, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.53% (May vary between batches)
Solubility
DMSO:62.5 mg/mL (209.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.7 mM)
Smiles
C[C@]12CCCN1Cc1n[nH]c (=O) c3cc (F) cc4[nH]c2c1c34
Molecular Formula
C16H15FN4O
Molecular Weight
298.31
Storage Conditions
-20°C
Notes
For research use only.
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