Pim1/AKK1-IN-1
Pim1/AKK1-IN-1 is a potent dual inhibitor of LKB1 and AAK1 with additional activity against Pim1, MST2, MPSK1, and TNIK kinases. This multi-kinase inhibitor is a valuable chemical probe for studying signaling pathways in cancer and neurological research, applicable in both in vitro and cellular assay systems.
Product Specifications
CAS Number
1093222-27-5
Product Name Alternative
Pim, Pim kinases, Pim1, Pim1/AKK1 IN 1, Pim1/AKK1IN1, Pim-1/AKK1-IN-1, Pim1/AKK1-IN-1, MDK 2275, MDK2275, MDK-2275, Hippopathway, Hippo pathway, Inhibitor, inhibit, LKB1/AAK1 dual inhibitor, MST2
Field of Research
Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.89 mM) ; DMSO:15 mg/mL (44.2 mM)
Smiles
O=C (Nc1c[nH]c2ncc (cc12) -c1ccc (cc1) C#N) c1cccnc1
Molecular Formula
C20H13N5O
Molecular Weight
339.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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